Gene interactions and pathways from curated databases and text-mining

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CREB5 — TRH

Text-mined interactions from Literome

Luo et al., Brain Res 1999 : To determine whether c-fos/c-jun ( AP-1 ) and CREB mediate glucocorticoid stimulated TRH gene regulation, we investigated the effect of N-ethyl-maleimide ( NEM ), an alkylating agent, and 12-O-tetradecanoylphorbol-13-acetate ( TPA ) on this process
Sarkar et al., Brain Res 2002 : These data demonstrate that i.c.v. alpha-MSH administration increases the phosphorylation of CREB in several subdivisions of the PVN including TRH and CRH neurons in the medial and periventricular parvocellular subdivisions, suggesting that phosphorylation of CREB may be necessary for alpha-MSH induced activation of the TRH and CRH genes
Chiappini et al., Mol Cell Endocrinol 2013 : To evaluate the role of CREB in TRH regulation in vivo, we deleted CREB from PVN neurons to generate the CREB1 ( dSIM1 ) mouse