Gene interactions and pathways from curated databases and text-mining

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ITGB6 — MMP9

Text-mined interactions from Literome

Agrez et al., Int J Cancer 1999 (Colonic Neoplasms) : The alpha v beta 6 integrin induces gelatinase B secretion in colon cancer cells
Bezuidenhout et al., Inflammation 2009 : Additionally, integrin beta(2) blockade significantly inhibited the Ang-2/PDGF-BB based increase in matrix metalloproteinase-9 (MMP-9) and membrane type-1-MMP (MT1-MMP)
Niu et al., Biochem Biophys Res Commun 1998 (Colonic Neoplasms) : Herein we report that the alpha v beta 6 integrin expressed in colon cancer cells induces gelatinase B secretion through the C-terminal cytoplasmic extension unique to the beta 6 integrin subunit, and that this ligand independent event involves activation of the protein-kinase-C pathway