Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
NKX2-1
→
MAPK1
(directlyIncreases, NKX2-1 Activity)
Missero et al., Mol Cell Biol 2000* Evidence: Indeed, ERK directly phosphorylates TTF-1 at three serine residues, and concomitant mutation of these serines to alanines completely abolishes ERK-mediated phosphorylation both in vitro and in vivo.
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *