Gene interactions and pathways from curated databases and text-mining

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EXO5 — RAD50

Text-mined interactions from Literome

Booth et al., Nucleic Acids Res 2001 : In contrast to an earlier model, our new results are consistent with a model in which a RAD24 dependent , 5 ' to 3 ' exonuclease moves from the telomere toward the centromere in cdc13-1 mutants
Constantinesco et al., Nucleic Acids Res 2004 : These results suggest that the archaeal Rad50-Mre11 complex might act in association with a 5 ' to 3 ' exonuclease ( NurA ) and a bipolar DNA helicase ( HerA ) indicating a probable involvement in the initiation step of homologous recombination
Dupré et al., Nat Chem Biol 2008 (Ataxia Telangiectasia) : Mirin prevents MRN dependent activation of ATM without affecting ATM protein kinase activity, and it inhibits Mre11 associated exonuclease activity