Satake et al., Pathol Int 2008
(Adenocarcinoma...) :
Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma
Shang et al., Neoplasia (New York, N.Y.) 2012
(Fallopian Tube Neoplasms...) :
Loss of either CLDN3 or CLDN4 resulted in down-regulation of E-cadherin mRNA and protein, increased inhibitory phosphorylation of glycogen synthase kinase-3ß ( GSK-3ß ), and activation of ß-catenin pathway signaling as evidenced by increases in nuclear ß-catenin, the dephosphorylated form of the protein, and transcriptional activity of ß-catenin/T-cell factor ( TCF )