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AR — PTEN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PTEN — AR (direct interaction, pull down) Lin et al., Mol Endocrinol 2004*
• IRef Biogrid Interaction: PTEN — AR (physical association, affinity chromatography technology) Lin et al., Mol Endocrinol 2004*
• IRef Hprd Interaction: AR — PTEN (in vivo) Lin et al., Mol Endocrinol 2004*
• IRef Hprd Interaction: AR — PTEN (in vitro) Lin et al., Mol Endocrinol 2004*

Text-mined interactions from Literome

Nan et al., J Mol Endocrinol 2003 : To investigate whether the tumor suppressor gene PTEN affects the activity of the androgen receptor (AR) , we monitored the expression of the apoptotic gene HA-Bax ( inserted in an adenovirus where it is driven by the AR-responsive promoter ARR(2)PB ) in the presence or absence of dihydrotestosterone, in PTEN ( + ) or ( - ) prostate cancer cell lines, infected with an adenovirus containing wild-type PTEN ( Av-CMV-PTEN ) or a control LacZ expressing construct
Wu et al., Prostate 2006 (Neoplasms, Hormone-Dependent...) : While the transcriptional activity of the androgen receptor (AR) is inhibited by PTEN in androgen sensitive prostate cancer ( CaP ), the role of PTEN in androgen disease is unclear
Ma et al., Mol Endocrinol 2009 : Our previous studies showed that the transcriptional activity of the androgen receptor (AR) was inhibited by PTEN in an AKT-sensitive manner
Wang et al., Oncogene 2011 (Breast Neoplasms...) : Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers