Liu et al., Mol Endocrinol 2005
:
Consistent with this corepressor function, depletion of endogenous mSin3A by small interfering RNA was sufficient to enhance prolactin gene expression by 70 %, comparable to the induction by the HDAC inhibitor, trichostatin A
Kabotyanski et al., Mol Endocrinol 2006
:
Prl alone resulted in a rapid recruitment of both signal transducer and activator of transcription 5 and histone deacetylase 1 to the beta-casein promoter and enhancer, and reciprocally the dissociation of Ying Yang-1 from the proximal promoter