◀ Back to CXCL12

CXCL12 — IL18

Text-mined interactions from Literome

Damås et al., Circulation 2002 (Angina, Unstable) : In vitro, SDF-1alpha ( 500 ng/mL ) reduced both unstimulated and endotoxin/mitogen stimulated mRNA and protein levels of monocyte chemoattractant protein-1, interleukin-8 , matrix metalloproteinase-9, and tissue factor while increasing tissue inhibitor of metalloproteinases-1 in PBMC from patients with unstable angina
Kanda et al., Eur J Immunol 2007 : IL-18 enhances IFN-gamma induced production of CXCL9, CXCL10 , and CXCL11 in human keratinocytes ... We examined the in vitro effects of IL-18 on IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production in human keratinocytes ... IL-18 enhanced the IFN-gamma induced secretion and mRNA expression of CXCL9, CXCL10 , and CXCL11 in parallel to the activation of NF-kappaB, STAT1, and IFN-regulatory factor (IRF)-1
Amin et al., Arthritis Rheum 2007 (Arthritis, Rheumatoid) : IL-18 significantly enhanced the production of SDF-1alpha/CXCL12 , MCP-1/CCL2, and VEGF in RA ST fibroblasts, in a time- and concentration dependent manner ... IL-18 induced SDF-1alpha/CXCL12 up-regulation was dependent on JNK, p38 MAPK, phosphatidylinositol 3-kinase (PI3K), and NFkappaB ... While IL-18 induced production of SDF-1alpha/CXCL12 was also dependent on protein kinase Cdelta (PKCdelta), production of MCP-1/CCL2 was dependent on PKCalpha, not PKCdelta