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IRF6 — RHOB
Text-mined interactions from Literome
Kamon et al., EMBO J 2006
:
LPS increased the activity of
RhoB , but not of RhoA, Cdc42, or Rac1/2 in a manor dependent on LPS-TRIF- but not LPS-Myd88 signaling ... Moreover, we found GEFH1 associated with RhoB, and DN-GEFH1 or GEFH1 's RNAi suppressed the
LPS mediated
RhoB activation and MHCII surface expression
Wang et al., J Physiol Biochem 2013
(Inflammation) :
The
upregulation of
RhoB by
LPS was also observed in mouse peritoneal macrophages and in mouse lung, liver, and kidney ... These results demonstrated that
LPS induced
RhoB expression in mouse in vivo and in vitro and in RAW264.7 cells, and the role of RhoB on LPS induced secretion of TNF-a and NO was at least partly mediated via NF-?B