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HRAS — SLC2A4RG
Text-mined interactions from Literome
Gotoh et al., J Biol Chem 2000
(Breast Neoplasms) :
In contrast to several other Ral-GEFs, the Ral
GEF activity of AND-34 is not
augmented by constitutively active
Ha-Ras ( Val-12 ), consistent with the absence of a detectable Ras binding domain
Keiper et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
Finally, we have demonstrated that activation of H-Ras and ERK1/2 requires the lipase activity of PLC-epsilon and the subsequent [ Ca2+ ] i increase, suggesting that
H-Ras activation is
mediated by a Ca2+ -activated
GEF
Rubio et al., Biochem J 2006
(MAP Kinase Signaling System) :
Using a cell-permeabilization approach to monitor nucleotide exchange on Ras, we demonstrate that PE-induced
Ras-GTP accumulation
results from
GEF stimulation