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CDH1 — PFKFB3
Text-mined interactions from Literome
Herrero-Mendez et al., Nat Cell Biol 2009
:
Upregulation of
Pfkfb3 by either inhibition of
Cdh1 or overexpression of Pfkfb3 in neurons resulted in the activation of glycolysis
Moncada et al., Biochem J 2012
:
APC/C ( anaphase promoting complex/cyclosome )
-Cdh1 , the ubiquitin ligase that controls G ( 1 ) - to S-phase transition by targeting specific degradation motifs in cell-cycle proteins, also
regulates the glycolysis promoting enzyme
PFKFB3 ( 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 ) and GLS1 ( glutaminase 1 ), a critical enzyme in glutaminolysis