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CTTN — RAC2

Text-mined interactions from Literome

Di Ciano et al., Am J Physiol Cell Physiol 2002 : This appears to be a key event in the osmotically triggered cytoskeletal reorganization, because 1 ) constitutively active small GTPases translocate cortactin, 2 ) Rac and cortactin colocalize at the periphery of hypertonically challenged cells, and 3 ) dominant negative Rac and Cdc42 inhibit the hypertonicity provoked cortactin and Arp3 translocation
El Sayegh et al., Mol Biol Cell 2005 : We conclude that N-cadherin ligation induces Rac dependent cortactin recruitment and Fer dependent cortactin phosphorylation, which in turn promotes enhanced mobilization and interaction of surface expressed N-cadherin in contacting cells
Birukova et al., FASEB J 2007 : The pharmacological Rac inhibitor or silencing RNA ( siRNA ) based depletion of either Rac or Tiam1 significantly attenuated HGF induced peripheral translocation of Rac effector cortactin , cortical actin ring formation, and EC barrier enhancement