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CD14 — TLR3
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
CD14
→
TLR3
(reaction)
Kishimoto et al., J Biol Chem 2000, Kalai et al., Cell Death Differ 2002, Donepudi et al., Mol Cell 2003, Fitzgerald et al., Nat Immunol 2003, Mori et al., J Biol Chem 2004, Kaiser et al., J Immunol 2005, Sato et al., Nat Immunol 2005, Shim et al., Genes Dev 2005, Adhikari et al., Oncogene 2007, Panne et al., J Biol Chem 2007, Keller et al., Structure 2009, Oberst et al., J Biol Chem 2010, Feoktistova et al., Mol Cell 2011, Estornes et al., Cell Death Differ 2012
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Farnell et al., Dev Comp Immunol 2003
:
Oxidative burst
mediated by
toll like receptors ( TLR ) and
CD14 on avian heterophils stimulated with bacterial toll agonists
Lucarelli et al., Eur Cytokine Netw 2004
:
On the other hand,
TLR9 expression was decreased by SiO ( 2 ) nano-particles, and expression of the co-receptor
CD14 was
inhibited by Co nanoparticles
Lee et al., Immunity 2006
:
Double stranded RNA mediated
TLR3 activation is
enhanced by
CD14 ... Here, we show that
CD14 enhances double stranded RNA ( dsRNA ) -mediated
Toll-like receptor 3 (TLR3) activation ... Consequently,
CD14 mediates pIpC uptake and
enhances TLR3 signaling
Roncon-Albuquerque et al., Life Sci 2008
(Fatty Liver...) :
These results suggest that
CD14 mediated
TLR activation might contribute to the cardiovascular and metabolic complications of obesity
Jia et al., Shanghai Kou Qiang Yi Xue 2011
:
CD14,
TLR4 receptors are involved in P.e-LPS effect and
CD14 , TLR2 and TLR4 receptors are
involved in P.g-LPS effect in mouse osteoblast
Lei et al., J Med Primatol 2013
:
Toll-like receptor ( TLR ) stimulation significantly
increased IDO protein level in
CD14 ( + ), CD56 ( + ), CD1c ( + ), CD11c ( + ), and CD123 ( + ) myeloid cells