Gene interactions and pathways from curated databases and text-mining

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FAS — SP1

Text-mined interactions from Literome

MagaƱa et al., J Biol Chem 2000 : In contrast, carbohydrate activation of the FAS promoter in primary hepatocytes is dependent upon SREBP and both the Sp1 and CCAAT binding factor/nuclear factor Y sites
Lu et al., Int J Cancer 2010 (Neoplasms) : Only Sp1 , however, also regulates FAS
Bennett et al., J Biol Chem 1995 : It is also demonstrated that SREBP and Sp1 synergistically activate the FAS promoter in Drosophila tissue culture cells, which lack endogenous Sp1