Gene interactions and pathways from curated databases and text-mining

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CXCL1 — FOS

Text-mined interactions from Literome

Wang et al., Oncogene 2000 (Cell Transformation, Neoplastic...) : The effects of MGSA/GRO on AP-1 activation could be mimicked by over-expression of wild-type M-Ras or a constitutively activated M-Ras mutant in control melan-a cells as monitored by an AP-1-luciferase reporter, while expression of a dominant negative M-Ras blocked AP-1-luciferase activity in MGSA/GRO transformed melan-a clones
Cinatl et al., Int J Mol Med 2005 (Colonic Neoplasms...) : High hydrocortisone concentrations ( > or =50 microg/ml ) completely prevented increased DNA binding activity of AP-1 and NF-kappaB and inhibited up-regulation of CXCL8 and CXCL10, but did not reduce chemokine expression to basal levels
D'Aversa et al., J Neurosci Res 2008 (AIDS Dementia Complex...) : Gel shift analyses demonstrated that NFkappaB and AP-1 , but not C/EBPbeta, mediate microglial CXCL8 production