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EGFR — ROCK2

Text-mined interactions from Literome

Ohtsu et al., Arterioscler Thromb Vasc Biol 2005 (Cardiovascular Diseases) : We have further demonstrated that the Rho/ROCK activation by Ang II requires protein kinase C-delta (PKCdelta) and proline-rich tyrosine kinase 2 (PYK2) activation, but not epidermal growth factor receptor transactivation
Samarakoon et al., J Mol Cell Cardiol 2008 : Thus, two distinct pathways involving the EGFR/pp60(c-src)/MEK-ERK pathway and Rho/ROCK dependent SMAD2 activation are required for TGF-beta1 induced PAI-1 expression in VSMC
Nakashima et al., Molecular cancer 2011 (Carcinoma...) : While EGF first stimulates the activation of the EGFR and subsequently increases cancer cell proliferation, EGF concurrently induces the activation of ROCK , which then turns off the activated EGFR pathway via a negative feedback system
Jeong et al., Mol Oncol 2013 (Ovarian Neoplasms) : Further we provide evidence that resveratrol inhibits EGFR phosphorylation and subsequent activation of a Ras/Rho/ROCK signaling