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EPO — SLC22A3

Text-mined interactions from Literome

Chen et al., Exp Cell Res 2010 : In contrast, EPO reversed TGF-beta1 mediated apoptosis and also partially inhibited TGF-beta1 mediated EMT ... Inhibition of mitogen activated protein kinase kinase 1 ( MEK 1 ) either directly with PD98059 or with MEK 1 siRNA resulted in inhibition of EPO mediated suppression of EMT and Smad signal transduction in TGF-beta1 treated cells ... EPO inhibited apoptosis and EMT in TGF-beta1 treated LLC-PK1 cells
Morais et al., BMC cancer 2013 (Anemia...) : EPO may also stimulate epithelial-mesenchymal transition (EMT) in RCC, and pathological EMT has a key role in cancer progression