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BCL10 — CARD9

Pathways - manually collected, often from reviews:

• KEGG Tuberculosis: Complex of BCL10-CARD9-MALT1 → NFKB1/RELA (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: BCL10 — CARD9 Bertin et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: BCL10 — CARD9 (coimmunoprecipitation) Bertin et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: BCL10 — CARD9 (two hybrid) Bertin et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: BCL10 — CARD9 (imaging technique) Bertin et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: BCL10 — CARD9 (affinity chromatography technology) Bertin et al., J Biol Chem 2000*
• IRef Biogrid Interaction: BCL10 — CARD9 (direct interaction, two hybrid) Bertin et al., J Biol Chem 2000*
• IRef Biogrid Interaction: BCL10 — CARD9 (physical association, affinity chromatography technology) Bertin et al., J Biol Chem 2000*
• IRef Biogrid Interaction: BCL10 — CARD9 (direct interaction, pull down) Bertin et al., J Biol Chem 2000*
• IRef Hprd Interaction: BCL10 — CARD9 (in vivo) Bertin et al., J Biol Chem 2000*
• IRef Hprd Interaction: BCL10 — CARD9 (in vitro) Bertin et al., J Biol Chem 2000*
• IRef Innatedb Interaction: BCL10 — CARD9 (unknown, -) Bertin et al., J Biol Chem 2000*
• IRef Intact Interaction: Complex of 16 proteins (association, anti bait coimmunoprecipitation) Gringhuis et al., Nat Immunol 2012*
• IRef Intact Interaction: Complex of MALT1-CARD9-CASP8-BCL10-CARD9-MALT1-BCL10-CASP8 (association, anti bait coimmunoprecipitation) Gringhuis et al., Nat Immunol 2012*
• IRef Intact Interaction: Complex of BCL10-MALT1-CARD9-CARD9-MALT1-CARD9-BCL10-MALT1-BCL10 (association, anti bait coimmunoprecipitation) Gringhuis et al., Nat Immunol 2012*
• IRef Ophid Interaction: BCL10 — CARD9 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Yan et al., J Biol Chem 1999 : Mutational analysis indicates that CARD mediated mE10 oligomerization is essential for killing activity
Bertin et al., J Biol Chem 2000 : We propose here that CARD9 is an upstream activator of BCL10 and NF-kappaB signaling
Bertin et al., J Biol Chem 2001 : When expressed in cells, CARD11 and CARD14 activate NF-kappaB and induce the phosphorylation of BCL10
Langel et al., J Biol Chem 2008 : We now provide evidence that the death domain of MALT1 and the CARD of Bcl10 also contribute to Bcl10-MALT1 interactions