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CCR2 — IFNG
Text-mined interactions from Literome
Hu et al., J Immunol 2005
(Inflammation) :
IFN-gamma primed macrophages exhibit increased
CCR2 dependent migration and altered
IFN-gamma responses mediated by Stat1
Goodyear et al., J Immunol 2010
(Burkholderia Infections...) :
Production of IL-12 and
IFN-gamma in the lungs after B. mallei infection was significantly
impaired in both MCP-1 ( -/- ) and
CCR2 ( -/- ) mice, whereas treatment of CCR2 ( -/- ) mice with rIFN-gamma restored protection against lethal challenge with B. mallei
Penton-Rol et al., J Immunol 1998
:
IFN-gamma selectively and rapidly
inhibited expression of the monocyte chemotactic protein (MCP) receptor
CCR2 with an ED50 of approximately 50 U/ml ... Thus,
IFN-gamma , an inducer of MCP-1 and MCP-3 in mononuclear phagocytes, selectively
inhibits expression of the MCP receptor
CCR2 in monocytes
Zella et al., Blood 1998
:
Interferon-gamma increases expression of chemokine receptors CCR1,
CCR3 , and CCR5, but not CXCR4 in monocytoid U937 cells