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NPY6R — PTK2
Text-mined interactions from Literome
Zhu et al., Structure 1999
:
We report here the high-resolution crystal structures of an activated Lck kinase domain in complex with three structurally distinct ATP-competitive inhibitors : AMP-PNP ( a non-selective, non-hydrolyzable ATP analog ) ; staurosporine ( a potent but non-selective protein kinase inhibitor ) ; and
PP2 ( a potent Src family selective
protein tyrosine kinase inhibitor )
Ding et al., J Biochem 2000
:
The tyrosine phosphorylation of wild-type Syk and mSH2 ( C ) Syk, but not that of mSH2 ( N ), was sensitive to
PP2 , a specific
inhibitor of Src-family
protein-tyrosine kinase
Hinata et al., J Pharmacol Sci 2007
:
On the other hand, wortmannin, a phosphatidylinositol 3-kinase (PI3K) inhibitor, inhibited only the NHE dependent pathway, while
PP2 , a Src family
protein tyrosine kinase inhibitor , inhibited only the NHE independent pathway
Oyaizu et al., Intensive Care Med 2012
(Acute Lung Injury...) :
The gene expression profiles and Src protein tyrosine kinase ( PTK ) phosphorylation were studied over time, and
PP2 , an Src
PTK inhibitor , was intravenously administered 10 min before lung ischemia to determine the role of Src PTK in lung injury