Gene interactions and pathways from curated databases and text-mining

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HIF1A — IFI44

Text-mined interactions from Literome

Yoo et al., J Biol Chem 2003 (Anoxia...) : Second, HBx induced both phosphorylation of HIF-1alpha and activation of p42/p44 mitogen activated protein kinases ( MAPKs ), which were synergistically enhanced in the presence of CoCl2
Li et al., Clin Cancer Res 2004 (Anoxia...) : Additional analyses using LY294002 and U0126 indicated that the increase in hypoxia-inducible factor 1 (HIF-1)alpha protein level was highly dependent on phosphatidylinositol 3'-kinase and p42/p44 mitogen activated protein kinase activities in hypoxic MDA-MB-468 cells
Lee et al., Clin Cancer Res 2006 (Neoplasm Invasiveness...) : In OVCAR-3 and PC-3 cells, the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin/p70S6K and p42/p44 mitogen activated protein kinase pathways were required for LPA induced HIF-1alpha and VEGF expressions, whereas only the phosphoinositide 3-kinase/mammalian target of rapamycin/p70S6K pathway was important in SK-Hep1 cells