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EGFR — MYLIP

Text-mined interactions from Literome

Adams et al., Mol Endocrinol 2009 (Breast Neoplasms) : Furthermore, EGF treatments enhanced miR-206 levels in MCF-7 cells and ERalpha negative, EGFR positive MDA-MB-231 cells, whereas EGFR small interfering RNA, or PD153035, an EGFR inhibitor, or U0126, a MAPK kinase inhibitor, significantly reduced miR-206 levels in MDA-MB-231 cells
Cowden Dahl et al., Neoplasia (New York, N.Y.) 2009 (Disease Progression...) : We report that EGFR signaling leads to transcriptional repression of the miRNA miR-125a through the ETS family transcription factor PEA3
du Rieu et al., Clin Chem 2010 (Adenocarcinoma...) : miR-21 production was regulated by KRAS ( G12D ) and epidermal growth factor receptor in PDAC derived cell lines
Zhu et al., Mol Cancer Res 2011 (Colitis, Ulcerative...) : Effects of EGFR on miR-143 and miR-145 expression were assessed in murine and human colonic cells and their putative targets examined in vitro and in vivo ... EGFR suppresses miR-143 and miR-145 in murine models of colon cancer
Mei et al., Mol Cell Biol 2011 (Glioma) : Our global expression analysis for microRNAs revealed that EGFR activation induces miR-146a expression, which is further potentiated by inactivation of PTEN
Kalinowski et al., PloS one 2012 (Head and Neck Neoplasms) : Several studies have demonstrated that microRNA-7 (miR-7) regulates EGFR expression and Akt activity in a range of cancer cell types via its specific interaction with the EGFR mRNA 3'-untranslated region ( 3'-UTR )
Kang et al., PloS one 2013 (Carcinoma, Non-Small-Cell Lung...) : We elected to validate our model in vitro by testing the effects of EGFR inhibition on downstream MYC, miR-9 and let-7a expression
Chen et al., PloS one 2013 (Carcinoma, Non-Small-Cell Lung...) : In functional experiments, miR-146a suppressed cell growth, induced cellular apoptosis and inhibited EGFR downstream signaling in five NSCLC cell lines ( H358, H1650, H1975, HCC827 and H292 )
Acunzo et al., Proc Natl Acad Sci U S A 2013 (Carcinoma, Non-Small-Cell Lung...) : We show that miR-27a regulates MET, EGFR , and Sprouty2 in lung cancer ... In addition, we identify both direct and indirect mechanisms by which miR-27a can regulate both MET and EGFR
Cui et al., FEBS J 2013 (Breast Neoplasms) : Bioinformatics prediction showed that epidermal growth factor receptor (EGFR) is a potential target for miR-133a ... These results demonstrate that miR-133a , which may act as a tumor suppressor in breast cancer, regulates the cell cycle and proliferation in tumorigenesis by targeting EGFR through the downstream signal molecule Akt