Gene interactions and pathways from curated databases and text-mining

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PLAT — PRL

Text-mined interactions from Literome

Tonner et al., Adv Exp Med Biol 2000 : In support of this hypothesis we have shown that both prolactin and GH inhibit tPA activity and plasminogen activation in the involuting mammary gland
Liu et al., Sheng Li Xue Bao 1998 : This study was designed to investigate whether prolactin (PRL) affects coordinated regulation of tissue plasminogen activator (tPA) and plasminogen activator inhibitor type-I ( PAI-I ) gene expression in rat granulosa cells in vitro ... Several methods, such as SDS-PAGE, immunoblot etc. were used to detect the effect of PRL on tPA and PAI-I gene expression
Flint et al., J Mol Endocrinol 2006 : PRL inhibited gene expression of matrix metalloproteinases ( MMPs ) 3 and 12 but not tissue plasminogen activator or plasmin in wild-type and transgenic animals
Liu et al., Hum Reprod 1997 : PRL also suppressed HCG induced tPA gene expression in a dose- and time dependent manner