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Kähler et al., Exp Lung Res 2001
:
We examined the
effect of SP, VIP and the novel sensory neuropeptide secretoneurin ( SN ), as well as of interleukin (IL)-8, IL-6,
IL-1 beta , transforming growth factor ( TGF ) -beta, and tumor necrosis factor (TNF), all associated with acute lung injury, on human
neutrophil migration across a 5-mu pore polycarbonate filter system covered by human lung fibroblast monolayers
Silva et al., J Dent Res 2005
:
Dentin sialoprotein (DSP) and dentin phosphoprotein ( DPP ), the major dentin proteins, have been shown to
induce neutrophil migration through release of
IL-1beta , TNF-alpha, MIP-2, and KC
Oliveira et al., Inflammation 2008
:
In the present study, we investigate whether mast cells and macrophages are involved in the control of
IL-1beta induced
neutrophil migration , as well as the participation of chemotactic mediators ...
IL-1beta induced a dose dependent neutrophil migration to the peritoneal cavity of rats which depends on LTB ( 4 ), PAF and cytokines, since the animal treatment with inhibitors of these mediators ( MK 886, PCA 4248 and dexamethasone respectively ) inhibited IL-1beta induced
neutrophil migration ... The
neutrophil migration induced by
IL-1beta is dependent on mast cells and macrophages, since depletion of mast cells reduced the process whereas the increase of macrophage population enhanced the migration ... Moreover, mast cells or macrophages stimulated with IL-1beta released a neutrophil chemotactic factor, which mimicked the
neutrophil migration induced by
IL-1beta ... In conclusion, our results suggest that
neutrophil migration induced by
IL-1beta depends upon LTB ( 4 ) released by macrophages and upon IL-1beta and TNFalpha released by mast cells
Cunha et al., J Leukoc Biol 2008
(Hyperalgesia...) :
Conversely, hypernociception and
neutrophil migration induced by TNF-alpha,
IL-1beta , and CINC-1/CXCL1 was inhibited by fucoidin, suggesting that neutrophils are involved in the production of direct acting hypernociceptive mediators
Ribeiro et al., Immunology 1991
:
Pre-treatment of the animals with dexamethasone ( 0.5 mg/kg, s.c. ) or depletion of the peritoneal resident cell population abolished the
neutrophil migration induced by rIL-8 and by recombinant
interleukin-1 beta ( rIL-1 beta )
Nakamura et al., J Exp Med 2009
(Familial Mediterranean Fever...) :
Furthermore, MCs expressing disease associated but not wild-type NLRP3 secreted
IL-1beta and
induced neutrophil migration and vascular leakage, the histological hallmarks of urticarial rash, when transplanted into mouse skin
Faccioli et al., Agents Actions 1990
:
These results suggest that the
neutrophil migration induced by IL-1 alpha,
IL-1 beta , TNF alpha and TNF beta is not due to a direct effect on neutrophils, but occurs via the release of a chemotactic factor ( s ) from resident macrophages