Gene interactions and pathways from curated databases and text-mining

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IL1B — NM

Text-mined interactions from Literome

Kähler et al., Exp Lung Res 2001 : We examined the effect of SP, VIP and the novel sensory neuropeptide secretoneurin ( SN ), as well as of interleukin (IL)-8, IL-6, IL-1 beta , transforming growth factor ( TGF ) -beta, and tumor necrosis factor (TNF), all associated with acute lung injury, on human neutrophil migration across a 5-mu pore polycarbonate filter system covered by human lung fibroblast monolayers
Silva et al., J Dent Res 2005 : Dentin sialoprotein (DSP) and dentin phosphoprotein ( DPP ), the major dentin proteins, have been shown to induce neutrophil migration through release of IL-1beta , TNF-alpha, MIP-2, and KC
Oliveira et al., Inflammation 2008 : In the present study, we investigate whether mast cells and macrophages are involved in the control of IL-1beta induced neutrophil migration , as well as the participation of chemotactic mediators ... IL-1beta induced a dose dependent neutrophil migration to the peritoneal cavity of rats which depends on LTB ( 4 ), PAF and cytokines, since the animal treatment with inhibitors of these mediators ( MK 886, PCA 4248 and dexamethasone respectively ) inhibited IL-1beta induced neutrophil migration ... The neutrophil migration induced by IL-1beta is dependent on mast cells and macrophages, since depletion of mast cells reduced the process whereas the increase of macrophage population enhanced the migration ... Moreover, mast cells or macrophages stimulated with IL-1beta released a neutrophil chemotactic factor, which mimicked the neutrophil migration induced by IL-1beta ... In conclusion, our results suggest that neutrophil migration induced by IL-1beta depends upon LTB ( 4 ) released by macrophages and upon IL-1beta and TNFalpha released by mast cells
Cunha et al., J Leukoc Biol 2008 (Hyperalgesia...) : Conversely, hypernociception and neutrophil migration induced by TNF-alpha, IL-1beta , and CINC-1/CXCL1 was inhibited by fucoidin, suggesting that neutrophils are involved in the production of direct acting hypernociceptive mediators
Ribeiro et al., Immunology 1991 : Pre-treatment of the animals with dexamethasone ( 0.5 mg/kg, s.c. ) or depletion of the peritoneal resident cell population abolished the neutrophil migration induced by rIL-8 and by recombinant interleukin-1 beta ( rIL-1 beta )
Nakamura et al., J Exp Med 2009 (Familial Mediterranean Fever...) : Furthermore, MCs expressing disease associated but not wild-type NLRP3 secreted IL-1beta and induced neutrophil migration and vascular leakage, the histological hallmarks of urticarial rash, when transplanted into mouse skin
Faccioli et al., Agents Actions 1990 : These results suggest that the neutrophil migration induced by IL-1 alpha, IL-1 beta , TNF alpha and TNF beta is not due to a direct effect on neutrophils, but occurs via the release of a chemotactic factor ( s ) from resident macrophages