Zhang et al., Int J Cancer 2007
(Melanoma, Experimental) :
Therefore, TAP1 expression restores both antigen presentation and immunogenicity in B16F10 melanoma cells and concomitantly reduces immunosuppressive IL-10 production at the local tumor site, thereby increasing immunosurveillance mechanisms against tumors
Ressing et al., Semin Cancer Biol 2008
(Epstein-Barr Virus Infections) :
Viral-IL10 causes a reduction in mRNA levels of TAP1 and bli/LMP2, a subunit of the immunoproteasome