Gene interactions and pathways from curated databases and text-mining

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CXCL12 — ICAM1

Text-mined interactions from Literome

Li et al., Zhonghua Xue Ye Xue Za Zhi 2003 (Multiple Myeloma) : To investigate the effect of stromal cell derived factor-1alpha ( SDF-1alpha ) expression and its receptor CXCR4 on the biological behavior of multiple myeloma ( MM ) cells and on the expression of soluble intercellular adhesion molecule 1 ( ICAM-1 )
Tohyama et al., Mol Biol Cell 2003 : The K1097/K1099 mutation also impaired binding to ICAM-1 induced by TCR cross linking or SDF-1
Friedrich et al., J Mol Cell Cardiol 2006 : Within the same time period, SDF-1 mediates both ICAM-1/beta2- and VCAM-1/beta1-integrin dependent monocyte adhesion, which is significantly decreased in cells overexpressing dominant negative Rac1N17
Yu et al., J Reprod Immunol 2007 : After orchiectomy or ovariectomy, the expression of ICAM-1 , CXCL12 and P-selectin mRNA in the examined organs increased , except JAM-1 in male and CXCL12 in female
Tung et al., J Biomed Sci 2012 (Colonic Neoplasms) : Human CRC DLD-1 cells were used to study the effect of SDF-1 on intercellular adhesion molecule-1 ( ICAM-1 ) expression and cell adhesion to endothelium ... By using specific inhibitors and short hairpin RNA ( shRNA ), we demonstrated that the activation of ERK, JNK and p38 pathways is critical for SDF-1 induced ICAM-1 expression and cell adhesion ... Inhibition of Sp1, C/EBP-ß and NF-?B activations by specific siRNA blocked the SDF-1 induced ICAM-1 promoter activity and expression
Valignat et al., Biophys J 2013 : Primary T lymphocytes migrating on ICAM-1 in the presence of uniformly applied SDF-1a were also found to migrate against the direction of shear flow
Wong et al., Cell Mol Immunol 2013 : However, iE-DAP and MDP could significantly upregulate cell surface expression of CD18 and intercellular adhesion molecule (ICAM)-1 on eosinophils and ICAM-1 on BEAS-2B cells, as well as induce chemokines CCL2 and CXCL8 release in the coculture system ( all P < 0.05 )