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ATF1 — GRAP2
Text-mined interactions from Literome
Adachi et al., J Immunol 2000
:
SB202190, a p38 inhibitor, blocked
p38 dependent phosphorylation of
activating transcription factor-2
Ghosh et al., J Biol Chem 2002
:
1 ) Both RTK and GPCR agonists activate p38 MAPK and induce CRE promoter dependent transcription ; 2 ) both RTK and GPCR agonists
induce ATF-1 phosphorylation, and ATF-1 is a predominant member in the CRE-DNA complexes formed in response to these agents ; and 3 )
p38 MAPK dependent ATF-1 phosphorylation and CRE promoter mediated transcription are associated with GPCR agonist induced VSMC growth
Wright et al., J Biol Chem 2007
:
In the present study raising cytosolic calcium resulted in increases in phosphorylation of p38 mitogen activated protein kinase and
activating transcription factor-2 , which were
blocked by the calcium/calmodulin dependent protein kinase inhibitor KN93 and by the
p38 mitogen activated protein kinase inhibitor SB202190