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FZD7 — WNT16
Pathways - manually collected, often from reviews:
-
KEGG Wnt signaling pathway:
WNT1/WNT10A/WNT10B/WNT11/WNT16/WNT2/WNT2B/WNT3/WNT3A/WNT4/WNT5A/WNT5B/WNT6/WNT7A/WNT7B/WNT8A/WNT8B/WNT9A/WNT9B
→
FZD1/FZD10/FZD2/FZD3/FZD4/FZD5/FZD6/FZD7/FZD8/FZD9
(protein-protein, activation)
-
KEGG Melanogenesis:
WNT1/WNT10A/WNT10B/WNT11/WNT16/WNT2/WNT2B/WNT3/WNT3A/WNT4/WNT5A/WNT5B/WNT6/WNT7A/WNT7B/WNT8A/WNT8B/WNT9A/WNT9B
→
FZD1/FZD10/FZD2/FZD3/FZD4/FZD5/FZD6/FZD7/FZD8/FZD9
(protein-protein, activation)
-
KEGG Pathways in cancer:
WNT1/WNT10A/WNT10B/WNT11/WNT16/WNT2/WNT2B/WNT3/WNT3A/WNT4/WNT5A/WNT5B/WNT6/WNT7A/WNT7B/WNT8A/WNT8B/WNT9A/WNT9B
→
FZD1/FZD10/FZD2/FZD3/FZD4/FZD5/FZD6/FZD7/FZD8/FZD9
(protein-protein, activation)
-
KEGG Basal cell carcinoma:
WNT1/WNT10A/WNT10B/WNT11/WNT16/WNT2/WNT2B/WNT3/WNT3A/WNT4/WNT5A/WNT5B/WNT6/WNT7A/WNT7B/WNT8A/WNT8B/WNT9A/WNT9B
→
FZD1/FZD10/FZD2/FZD3/FZD4/FZD5/FZD6/FZD7/FZD8/FZD9
(protein-protein, activation)
-
WikiPathways ESC Pluripotency Pathways:
WNT3/WNT5B/WNT7A/WNT5A/WNT16/WNT10A/WNT7B/WNT2/WNT9B/WNT3A/WNT11/WNT4/WNT1/WNT6/WNT10B/WNT2B
→
Complex of 12 proteins
(activation)
-
WikiPathways Wnt Signaling Pathway and Pluripotency:
WNT9B/WNT4/WNT7B/WNT10B/WNT5B/WNT2B/WNT3A/WNT16/WNT7A/WNT2/WNT11/WNT1/WNT6/WNT5A/WNT10A/WNT3
→
FZD8/FZD7/FZD5/FZD1/FZD6/FZD3/FZD2/FZD10/FZD9/FZD4
(activation)
-
WikiPathways Wnt Signaling in Kidney Disease:
WNT1/WNT10A/WNT10B/WNT7A/WNT16/WNT6/WNT5A/WNT2B/WNT11/WNT4/WNT3A/WNT5B/WNT9B/WNT2/WNT3/WNT7B
→
FZD1/FZD8/FZD4/FZD2/FZD7/FZD9/FZD5/FZD6/FZD3
(activation)
-
WikiPathways Wnt Signaling in Kidney Disease:
WNT1/WNT10A/WNT10B/WNT7A/WNT16/WNT6/WNT5A/WNT2B/WNT11/WNT4/WNT3A/WNT5B/WNT9B/WNT2/WNT3/WNT7B
→
LRP5/LRP6/FZD1/FZD8/FZD4/FZD2/FZD7/FZD9/FZD5/FZD6/FZD3
(activation)
-
WikiPathways Association Between Physico-Chemical Features and Toxicity Associated Pathways:
WNT16
→
FZD1/FZD2/FZD3/FZD4/FZD5/FZD6/FZD7/FZD8/FZD9/FZD10
(activation)
Text-mined interactions from Literome
Abu-Elmagd et al., Dev Biol 2006
:
Frizzled7 mediates canonical
Wnt signaling in neural crest induction
Wei et al., Molecular cancer 2011
(Carcinoma, Hepatocellular...) :
Soluble
Frizzled-7 receptor
inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin
Randall et al., J Orthop Res 2012
:
Activation of noncanonical
Wnt signaling through overexpression of both the cell-surface Wnt receptor
Fzd7 and receptor associated protein Ror2 with addition of recombinant Wnt5a promotes the initiation of columnar architecture of growth plate chondrocytes in vitro, representing an important step toward growth plate regeneration