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CTNND1 — FYN

Pathways - manually collected, often from reviews:

• KEGG Adherens junction: FYN → CTNND1 (protein-protein, inhibition)
• NCI Pathway Database Posttranslational regulation of adherens junction stability and dissassembly: Fyn (FYN) → E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin complex (CDH1-CTNNB1-CTNNA1-CTNND1) (modification, activates)
  Castaño et al., Mol Cell Biol 2007*
  Evidence: assay
• NCI Pathway Database E-cadherin signaling in keratinocytes: Fyn (FYN) → p120 catenin (CTNND1) (modification, activates) Xie et al., Mol Biol Cell 2005, Calautti et al., J Cell Biol 1998
  Evidence: assay, physical interaction, other species

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: FYN — CTNND1 (direct interaction, enzymatic study) Martinez et al., J Cell Biol 2003*
• IRef Biogrid Interaction: FYN — CTNND1 (physical association, affinity chromatography technology) Piedra et al., Mol Cell Biol 2003

Text-mined interactions from Literome

Nishio et al., J Neurochem 2001 : These findings indicate that ethanol stimulates tyrosine phosphorylation of Cas in rat cerebellum and cerebral cortex, and that Fyn may be involved in the process
Huang et al., Int J Cancer 2008 (Ovarian Neoplasms) : Our study provides evidence that LPA induces junction dispersal in ovarian cancer SKOV3 cells by activating the Src family kinase Fyn and increasing its association with p120-catenin at the cell-cell junction
Manié et al., J Biol Chem 1997 : Cotransfection studies in COS-7 cells further indicated that Fyn/Cas physical interaction and Fyn mediated Cas phosphorylation required amino acids 638-889 in the C-terminal region of Cas