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EGFR — IRF6

Text-mined interactions from Literome

Shao et al., Proc Natl Acad Sci U S A 2003 : Knockdown of TACE inhibited PMA-, PA sup-, and LPS induced TGF-alpha shedding, EGFR phosphorylation, and mucin production
Kim et al., Am J Physiol Lung Cell Mol Physiol 2004 (Metaplasia) : In this study, we investigated the associations between lipopolysaccharide (LPS) induced goblet cell ( GC ) metaplasia and EGFR expression and the effects of MMP inhibitor ( MMPI )
Koff et al., J Immunol 2006 : Because epidermal growth factor receptor (EGFR) activation stimulates wound repair and because LPS activates EGFR , we hypothesized that LPS accelerates wound repair via a surface signaling cascade that causes EGFR phosphorylation
Lin et al., Toxicol Appl Pharmacol 2008 : LPS stimulated Src, PYK2, EGFR , and Akt phosphorylation and VCAM-1 expression were attenuated by the inhibitors of Src ( PP1 ), EGFR ( AG1478 ), PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), respectively, or transfection with siRNAs of Src or Akt and shRNA of p110
Finzi et al., J Immunol 2009 (Biliary Tract Neoplasms...) : LPS induced early phosphorylation of EGFR and ERK1/2 in both types of cells, which reached maximum levels within 30 min ( first phase )
Hsu et al., Lab Invest 2010 (Colitis) : Neutralizing antibodies to EGFR ligands were used to examine inhibition of LPS dependent EGFR activation
McElroy et al., PloS one 2012 : We hypothesized that EGFR is required for LPS induction of COX-2 expression ... EGFR tyrosine kinase inhibitors block LPS stimulation of mitogen activated protein kinase ERK, suggesting an important role of the MAPK/ERK pathway in EGFR mediated COX-2 expression ... Taken together, these data show that EGFR plays an important role in LPS-induction of COX-2 expression in enterocytes, which may be one mechanism for EGF in inhibition of NEC