Gene interactions and pathways from curated databases and text-mining

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JUN — RARB

Text-mined interactions from Literome

Soprano et al., J Cell Biochem 2000 : Murine RARbeta4 displays reduced transactivation activity, lower affinity for retinoic acid, and no anti-AP1 activity ... The results demonstrate that RARbeta1 , beta2, and beta3 bind RA with a similar K ( d ) value, have a similar EC ( 50 ) value in RA-dependent transactivation assays and inhibit AP1 activity to a similar level
De-Castro Arce et al., J Biol Chem 2004 : Because AP-1 activity was not irreversibly disturbed, but could be switched on through activation of the Jun N-terminal kinase pathway, a model for the transient activation of AP-1 even in the presence of RARbeta as repressor is suggested