Gene interactions and pathways from curated databases and text-mining

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NFKBIE — TNF

Text-mined interactions from Literome

Laskov et al., Eur Cytokine Netw 2005 (Burkitt Lymphoma...) : Our results thus show that in Ramos cells, TNF-alpha and CD40L have common, as well as differential, signaling effects on the IkappaBalpha, IkappaBbeta and IkappaBepsilon , which form inhibitory complex ( es ) with the NF-kappaB cytosolic proteins
Stefansson et al., J Biol Chem 2006 : Knockdown of PP6 or PP6R1 but not PP6R3 with siRNA significantly enhanced degradation of endogenous IkappaBepsilon in response to tumor necrosis factor-alpha
Stefansson et al., Biochemistry 2008 : Knockdown of PP6R1 or Ankrd28, but not PP6R3, produced equivalent enhancement of IkappaBepsilon degradation in response to TNFalpha