Cho et al., J Clin Endocrinol Metab 2004
:
Ginsenoside-Rb1 from Panax ginseng C.A. Meyer activates estrogen receptor-alpha and -beta, independent of ligand binding
Aniagu et al., Toxicology 2009
:
In HepG2 cells, the mRNA gene expression levels of p16, RB1 and N-cym were significantly down regulated by HBCD ( 0.03 ng/mL ) and E ( 2 ) ( 0.1 ng/mL ) while HBCD at 0.3 ng/mL, significantly down regulated the expression levels of N-cym, ERalpha and ERbeta genes
Caligiuri et al., Oncotarget 2013
(Breast Neoplasms) :
pRb controls Estrogen Receptor alpha protein stability and activity