Gene interactions and pathways from curated databases and text-mining

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SNAP25 — TP53

Text-mined interactions from Literome

Ishida et al., Mol Pharmacol 1999 : SNAP markedly stimulated DNA binding activity of p53
Gordon et al., J Leukoc Biol 2001 : SNAP significantly increased the expression of heme oxygenase 1 ( HSP-32 ), p53 , and bax but not bcl-2
Figueroa et al., J Neurosci Res 2006 : SNAP , an NO donor, induces apoptosis in these cells because it 1 ) increases the p53 and 2 ) induces cytochrome c release and activation of caspase-9 and caspase-3
Kitamura et al., Neurochem Int 1998 (Neuroblastoma) : However, these pretreatments did not change Bax protein level and SNAP induced p53 expression