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ERVK-6 — PI3
Text-mined interactions from Literome
Bingle et al., Am J Respir Cell Mol Biol 2001
:
Elafin , a low molecular-weight
proteinase inhibitor , is a member of the recently described trappin gene family
Régnauld et al., Oncogene 2002
(Neoplasm Invasiveness...) :
AGalpha ( olf ) -mediated invasion was abrogated by agonists of platelet activating factor receptors ( PAF-R ) and
protease activated receptors -1 (PAR-1) , pharmacological
inhibitors of
PI3'-Kinase ( wortmannin ), protein kinase C ( Gö6976 and GF109203X ), Rho GTPase ( C3T exoenzyme ), but was independent of protein kinase A. Accordingly, the invasive phenotype induced by AGalpha ( olf ) in HCT-8/S11 cells was reversed by the RhoA antagonist RhoD ( G26V )
van Ruissen et al., J Invest Dermatol 1998
:
In a culture model that mimics normal epidermal differentiation we found that low concentrations of sodium dodecyl sulfate could induce the expression of
SKALP , a
proteinase inhibitor that is not normally expressed in human epidermis but is found in hyperproliferative skin