Arakawa et al., Nat Rev Cancer 2004
(Colorectal Neoplasms...) :
Surprisingly, binding of netrin-1 to its receptors inhibits tumour suppressor p53 dependent apoptosis, and p53 is directly involved in transcriptional regulation of netrin-1 and its receptors
Wu et al., Neuroscience 2008
(Brain Infarction...) :
Ischemia induced p53 expression was attenuated by netrin-1 Lee et al., Brain Res Bull 2013
:
In addition, netrin-1 significantly inhibited CoCl2 induced p53 stability and UNC5B expression and CoCl2 induced caspase-3 activity and cell death ... In addition, netrin-1 significantly inhibited CoCl2 induced p53 stability and UNC5B expression and CoCl2 induced caspase-3 activity and cell death