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IFNG — MMP1

Text-mined interactions from Literome

Nold et al., Naunyn Schmiedebergs Arch Pharmacol 2003 : Whereas IL-18 and TNFalpha induced the protease, MMP-9 release was not mediated by IFNgamma
Martelli-Junior et al., J Periodontol 2003 (Fibromatosis, Gingival) : IFN-gamma reduced both type I collagen and Hsp47 expression, whereas it had a slight effect on the expression of MMP-1 and MMP-2
Zhou et al., J Biol Chem 2003 : IFNgamma induced MMP-1 in the presence of GM-CSF through the stimulation of TNFalpha production through a mechanism involving both p38 and ERK1/2 MAPKs, in which GM-CSF stimulated ERK1/2 whereas IFNgamma activated p38 ... In support of this conclusion TNFalpha neutralizing antibody and antibodies against TNF receptor I and -II blocked the induction of MMP-1 by GM-CSF and IFNgamma
Wang et al., World J Gastroenterol 2008 (Liver Cirrhosis) : Both Cpd 861 and IFN-gamma reduced the mRNA levels of collagen type III, MMP-2 and TGF-beta1
Nareika et al., Atherosclerosis 2009 (Atherosclerosis...) : High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity ... Results showed that high glucose and IFN gamma had a synergistic effect on the expression of MMP-1, MMP-9 and IL-1 beta ... Results showed that high glucose and IFN gamma had a synergistic effect on the expression of MMP-1 , MMP-9 and IL-1 beta ... High glucose also enhanced IFN gamma induced priming effect on lipopolysaccharide (LPS) stimulated MMP-1 secretion
Mann et al., Ann Otol Rhinol Laryngol 1995 (Carcinoma, Squamous Cell...) : Supernatants of HNSCC cell lines SCC-25 and FADU stimulated with interleukin (IL)-1 alpha and IL-1 beta demonstrated modest induction of 92 kd GL production by zymogram analysis when compared with controls ; IL-2, IL-6, and interferon-gamma had no consistent effect on MMP production
Varga et al., Adv Exp Med Biol 1996 : Supplementation with tryptophan completely overcame the inhibitory effects of interferon-gamma on MMP mRNA expression and metalloproteinase secretion into the media ... These results indicate that oxidative tryptophan metabolism mediates the effects of interferon-gamma on MMP gene expression in human fibroblasts