Gene interactions and pathways from curated databases and text-mining

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HMGB1 — MAP2K1

Text-mined interactions from Literome

Kalinina et al., Arterioscler Thromb Vasc Biol 2004 (Arteriosclerosis) : Inhibitors of MEK1/MEK2 , protein kinase C, and PI-3/Akt, which inhibit lysosomal degranulation and mRNA translation, attenuated cytokine induced HMGB1 secretion
Ding et al., J Trauma Acute Care Surg 2012 : The aim of this study was to explore the role of mitogen activated protein kinase kinase 6 ( MKK6 ) in the HMGB1 expression in pulmonary alveolar epithelial cells induced by mechanical stretch