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Yu et al., Biochem Pharmacol 2004
(Colonic Neoplasms) :
Our results demonstrate that in human colon cancer cells,
gastrin caused a rapid tyrosine phosphorylation of FAK,
paxillin , and p130 ( Cas ) by activation of CCK ( 2 ) receptor
Yu et al., Cancer Res 2011
(Colorectal Neoplasms...) :
short hairpin ( shRNA ) -mediated knockdown of Rgnef or FAK, or pharmacological inhibition of FAK activity, is sufficient to block
gastrin stimulated
paxillin phosphorylation, cell motility, and invadopodia formation in a manner dependent upon upstream cholecystokinin-2 receptor expression