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CDK1 — CDK4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of STRN3-CDK1-CDK4-PPP2R1B-RALA (association, anti tag coimmunoprecipitation) Sablina et al., Cell 2007
• IRef Intact Interaction: Complex of CDK4-CDK1-STRN3-PPP2R1A (association, anti tag coimmunoprecipitation) Sablina et al., Cell 2007
• IRef Intact Interaction: Complex of 22 proteins (association, anti tag coimmunoprecipitation) Sablina et al., Cell 2007

Text-mined interactions from Literome

González et al., J Biol Chem 2003 : We show in this work that the inhibition of Cdk4 ( 6 ) in Rb(-/-) 3T3 cells enhances the accumulation of the p27 ( kip1 ) cyclin dependent kinase inhibitor when these cells are induced into quiescence
Berthet et al., Cell division 2006 : Cdk2 and Cdk4 cooperatively control the expression of Cdc2
Lu et al., J Pharm Pharmacol 2007 : AOA-GMe induced cell cycle arrest in G0/G1 and blocked G1-S transition, which correlated well with marked decreases in levels of cyclin D, cyclin dependent kinase CDK4 and phosphorylated retinoblastoma protein, and increases in the cyclin dependent kinase inhibitor p15
Kang et al., Apoptosis 2012 : Cell cycle analysis indicated thioridazine induced the down-regulation of cyclin D1, cyclin A and CDK4 , and the induction of p21 and p27, a cyclin dependent kinase inhibitor