Gene interactions and pathways from curated databases and text-mining

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PHKA2 — RHOA

Text-mined interactions from Literome

Gakidis et al., J Cell Biol 2004 : beta2 induced activation of Cdc42, Rac1, and RhoA is defective in Vav1/3ko neutrophils, and phosphorylation of Pyk2 , paxillin, and Akt is also significantly reduced
Yoo et al., Am J Physiol Cell Physiol 2011 : Furthermore, we showed that RhoA and Rho associated kinase (ROCK) are involved in activation of Pyk2
Gadepalli et al., Arterioscler Thromb Vasc Biol 2012 (Carotid Artery Injuries...) : In addition, adenovirus mediated expression of dominant negative Pyk2 inhibited thrombin induced Grb2 associated binder protein 1, p115 rho guanine nucleotide exchange factor, Rac1, RhoA and Pak1 stimulation