Gene interactions and pathways from curated databases and text-mining

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CXCR3 — RHOA

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: RHOA → CXCR3 (increases, CXCR3 Activity, RHOA Activity) Robledo et al., J Biol Chem 2001*
    Evidence: the chemokine Mig, a ligand for CXCR3, activates the small GTPases RhoA and Rac1, induces a reorganization of the actin cytoskeleton, and triggers cell chemotaxis and modulation of integrin VLA-5- and VLA-4-dependent cell adhesion to fibronectin.