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BCL3 — IL1A

Text-mined interactions from Literome

Elliott et al., Arthritis Res Ther 2003 (Bone Neoplasms...) : We have shown previously that IL-1 induces expression of the inhibitor of NF-kappaB ( IkappaB ) family member Bcl-3 , and that this contributes to MMP-1 expression ... To quantify the effects of CDDO on IL-1 induced MMP-1, MMP-13 and Bcl-3 expression, we stimulated the chondrosarcoma cell line SW-1353 and human primary chondrocytes with IL-1, in the presence or absence of CDDO ... In human primary chondrocytes, IL-1 induced Bcl-3 expression was inhibited when cells were pretreated with CDDO
Wessells et al., J Biol Chem 2004 : Analysis of macrophages from p50 and BCL-3 knock-out mice revealed that both transcription factors negatively regulate TNFalpha expression and that BCL-3 inhibits IL-1alpha and IL-1beta