Gene interactions and pathways from curated databases and text-mining

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IRS2 — SREBF1

Text-mined interactions from Literome

Shimano et al., J Mol Med (Berl) 2007 (Insulin Resistance...) : Taken together, TFE3/Foxo1 and SREBP-1c reciprocally regulate IRS-2 expression and insulin sensitivity in the liver
Shimano et al., Diabetes Obes Metab 2007 : Activation of SREBP-1c by overnutrition also inhibits insulin receptor substrate-2 (IRS-2) and induces insulin resistance in the liver