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GFRA1 — NCAM2

Text-mined interactions from Literome

Paratcha et al., Cell 2003 : Association of NCAM with GFRalpha1 , a GPI anchored receptor for GDNF, downregulates NCAM mediated cell adhesion and promotes high-affinity binding of GDNF to p140 ( NCAM ), resulting in rapid activation of cytoplasmic protein tyrosine kinases Fyn and FAK in cells lacking RET, a known GDNF signaling receptor
Sjöstrand et al., J Biol Chem 2008 : GFRalpha1 promotes high affinity GDNF binding to NCAM and down-regulates NCAM mediated homophilic cell adhesion, but the mechanisms underlying these effects are unknown