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EPHB2 — HSP90AA1

Text-mined interactions from Literome

Dou et al., Acta Biochim Biophys Sin (Shanghai) 2005 : We showed that Hsp90 inhibitors reduce ERK phosphorylation without affecting the total ERK protein level
Koga et al., Proc Natl Acad Sci U S A 2006 : Hsp90 inhibition transiently activates Src kinase and promotes Src dependent Akt and Erk activation
Babchia et al., Invest Ophthalmol Vis Sci 2008 (Melanoma...) : The inhibition of HSP90 downregulated B-Raf, decreased cell proliferation, and reduced activation of MEK/ERK in uveal melanoma cell lines expressing WT B-Raf
Bisel et al., J Cell Biol 2008 : ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65
Hackl et al., Surgery 2010 (Acute Disease...) : Inhibition of HSP90 effectively diminished the constitutive phosphorylation of Akt, Erk , and STAT3 in PHHs. Conversely, inhibition of HSP90 significantly increased the expression of both VEGF and HGF mRNA, and induced HSP70 protein in PHH cultures in vitro
Bhat et al., Mol Immunol 2010 : Our results demonstrate that binding of CpG ODN ( 2007 ) to Hsp90 induces activation of ERK2 and AKT phosphorylation leading to the production of high levels of IFN-gamma, IL-6, MIP-3alpha and nitric oxide ( NO )
Colello et al., J Biol Chem 2012 (MAP Kinase Signaling System) : Integrins regulate microtubule nucleating activity of centrosome through mitogen activated protein kinase/extracellular signal regulated kinase kinase/extracellular signal regulated kinase ( MEK/ERK ) signaling