Gene interactions and pathways from curated databases and text-mining

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EPHB2 — RASGRP4

Text-mined interactions from Literome

Ebinu et al., Blood 2000 : Overexpression of RasGRP in T cells enhanced TCR-Ras-Erk signaling and augmented interleukin-2 secretion in response to calcium ionophore plus DAG analogues phorbol ester myristate or bryostatin-1
Jun et al., Mol Cell Biol 2013 (MAP Kinase Signaling System) : We previously described how RasGRP alone induces analog Ras-ERK activation while SOS and RasGRP cooperate to establish bimodal ERK activation