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EPHB2 — PPARA

Text-mined interactions from Literome

Kim et al., J Pharmacol Exp Ther 2003 (Neuroblastoma) : We also found that PPAR-gamma antagonist GW9662 ( 2-chloro-5-nitro-N-phenylbenzamide ) reversed the 15-deoxy-PGJ2 induced cell growth inhibition, PPAR-gamma expression, and activation of ERK2
Lin et al., Cell Signal 2011 (Carcinoma, Non-Small-Cell Lung) : In addition, activation of P(38) instead of ERK played a critical role in TGFß induced expression of PPAR? , which subsequently activated RhoA in H460 cell
Huang et al., FASEB J 2011 : Exposure to HIV-1 infected monocytes induced phosphorylation of ERK1/2 and Akt in hCMEC by 2.5- and 3.6-fold, respectively ; however, these effects were attenuated by overexpression of PPARa or PPAR? and by silencing of caveolin-1 ( cav-1 )
Stachowska et al., J Agric Food Chem 2011 (MAP Kinase Signaling System) : PPAR? was phosphorylated mainly by ERK1/2 , and consequently, PPAR? phosphorylation was suppressed mainly by cis-9,trans-11 isomer
Duan et al., J Biol Chem 2012 : However, PPAR? activation by ligands or ERK1/2 inhibitors induced hepatic LDLR expression
Wang et al., PPAR research 2012 : Leptin treatment also leads to a mild downregulation of PPAR mRNA expression and a significant MAPK/ERK dependent PPAR? phosphorylation at serine 112/82
Mahali et al., Biochem Pharmacol 2012 (Diabetes Complications) : Only mangiferin, a ß-D-glucoside, prevented AGE mediated decrease in PPAR? activity and inhibited phosphorylation of ERK and cytoplasmic translocation of PPAR?
Morgenweck et al., Neuropharmacology 2013 (Ataxia...) : We conclude that pioglitazone reduces spinal glial and stimulus evoked p-ERK activation and that PPAR? activation blocks the development of and reduces established neuropathic pain