Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MAP3K3

Text-mined interactions from Literome

Adams et al., Arch Biochem Biophys 2002 : However, neither of these phosphorylated amino acids is required for association with 14-3-3 protein or regulation of MEKK3 dependent ERK and JNK activity
Xu et al., J Biol Chem 2004 : Expression of dominant negative mutants of MEKK2 and MEKK3 also blocked activation of ERK5 by WNK1
Fritz et al., J Biol Chem 2006 : MEKK3 dependent activation of an NF-kappaB reporter gene as well as ERK , JNK, and p38 MAP kinases correlated with a requirement for serine at position 526
Wang et al., J Biol Chem 2006 : Our evidence also indicates that Ras and MEKK3 , a MEK5 kinase in non-neuronal cells, do not play a significant role in BDNF activation of ERK5
Deng et al., Am J Physiol Cell Physiol 2007 (Neoplasms, Experimental...) : We also found that MEKK3 is required for angiopoietin-1 (Ang1) induced p38 and ERK5 activation
Hebron et al., Br J Haematol 2013 (Multiple Myeloma...) : In myeloma tumour cells, MAP3K8 acts as mitogen induced MAP3K in mitosis and is required for TNFa mediated ERK activation