Gene interactions and pathways from curated databases and text-mining

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CD40 — TLR5

Text-mined interactions from Literome

Funderburg et al., Proc Natl Acad Sci U S A 2007 : Here, we show that human beta-defensin-3 (hBD-3), an innate antimicrobial peptide, can induce expression of the costimulatory molecules CD80, CD86, and CD40 , on monocytes and myeloid dendritic cells in a TLR dependent manner
Movita et al., J Leukoc Biol 2012 : Interestingly, despite expression of TLR mRNA on Kupffer cells, ligation of TLR4, TLR7/8 , and TLR9 resulted in a weak induction of IL-10, low or undetectable levels of IL-12p40 and TNF, and up-regulation of CD40 on the surface
Ori et al., J Immunol 2013 : TAB2 and TAB3 are critical for the activation of MAPKs, especially ERK, but not NF-?B, in response to TLR and CD40 stimulation in B cells